Cardiological Screening In Young Oncological Convalescents Before Sport Participation By Heart Rate Variability Analysis
Vol.4,No.2(2010)
Young convalescents after oncological treatment are at risk of toxic cardiomyopathy development. An evaluation of their capability to an exercise or sport needs examination of heart state. Goal of work: To evaluate the heart rate variability (HRV) analysis as a screening method in early diagnostics of toxic cardiomyopathy by patients after oncological chemotherapy in childhood. The study was designed as an individual correlation test of HRV parameters to echocardiographical values. Probands: 85 girls and boys after oncological treatment by doxorubicin and/or cyclophosphamid; aging 7-29 years. Heart rate (beat to beat) was monitored during 5 minutes of vertical position, and in upright position. The echocardiographical measurement was performed at rest and after dynamic exercise. The values of the HRV parameters have no normal distribution. It was found that there was a close relationship of the rest ejection fraction to 3 HRV parameters – to spectral power of HF band in lying position and to MSSD in lying and in standing positions. Both of the last HRV parameters represent above all a vagal activity. It was found that there was a close relationship of after-stress ejection fraction to only one HRV parameter – to VLF/LF spectral power rate in lying position. Close associations were found in the difference of the rest – after-stress EF (d-EF) to seven HRV parameters in lying position. Therefore, it is believed that HRV analysis, as an instrumental, timing and personal less demanding method, can be used for cardiomyopathy screening in oncological paediatric patients before exercise and sport practise.
heart rate variability; cardiomyopathy; oncological therapy; exercise; sport
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